Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dipyridamole
Drug ID BADD_D00692
Description A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Indications and Usage For as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement and also used in prevention of angina.
Marketing Status approved
ATC Code B01AC07
DrugBank ID DB00975
KEGG ID D00302
MeSH ID D004176
PubChem ID 3108
TTD Drug ID D0F9GE
NDC Product Code 0641-2569; 65015-782; 65404-005; 66039-917; 68382-187; 0527-1463; 71205-895; 0115-1070; 0115-1071; 0115-1072; 51407-627; 62559-237; 69584-183; 0527-1461; 51407-626; 65841-662; 62559-236; 64980-133; 65841-663; 65841-664; 69584-182; 51407-628; 51662-1447; 0404-9852; 62559-235; 68382-188; 69584-181; 17511-122; 64980-134; 51927-1571; 68166-003; 71205-894; 71205-896; 64980-135; 68382-189; 0527-1462; 12660-0084
UNII 64ALC7F90C
Synonyms Dipyridamole | Dipyramidole | Apo-Dipyridamole | Apo Dipyridamole | Cerebrovase | Persantine | Persantin | Curantil | Curantyl | Kurantil | Miosen | Novo-Dipiradol | Novo Dipiradol | Antistenocardin | Cléridium
Chemical Information
Molecular Formula C24H40N8O4
CAS Registry Number 58-32-2
SMILES C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nausea07.01.07.0010.008102%
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.003--Not Available
Oedema08.01.07.006; 14.05.06.010--Not Available
Orthostatic hypotension24.06.03.004; 17.05.01.020--Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.0100.004978%
Palpitations02.11.04.012--
Pancreatitis07.18.01.001--
Paraesthesia23.03.03.094; 17.02.06.005--
Peptic ulcer07.04.07.001--Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pleuritic pain22.12.01.007--
Proctalgia07.03.02.001--
Pruritus23.03.12.001--
Pulmonary oedema22.01.03.003; 02.05.02.003--
Pyrexia08.05.02.0030.000976%
Rash23.03.13.001--Not Available
Rash erythematous23.03.13.029--Not Available
Renal pain20.02.03.003--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Seizure17.12.03.001--
Shock24.06.02.002--Not Available
Sinus arrest02.03.03.007--Not Available
Skin disorder23.03.03.007--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Supraventricular tachycardia02.03.03.012--
Syncope02.11.04.015; 24.06.02.012; 17.02.04.0080.000976%
Tachycardia02.03.02.007--Not Available
Tension19.06.02.005--Not Available
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