Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dobutamine hydrochloride
Drug ID BADD_D00698
Description A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Indications and Usage Indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
Marketing Status approved
ATC Code C01CA07
DrugBank ID DB00841
KEGG ID D00632
MeSH ID D004280
PubChem ID 65324
TTD Drug ID D0J7RK
NDC Product Code 0338-1073; 0338-1075; 14335-170; 0338-1077; 12711-4820; 51662-1566
UNII 0WR771DJXV
Synonyms Dobutamine | Dobucor | Dobuject | Dobutamin Fresenius | Dobutamin Hexal | Dobutamin Solvay | Dobutamin-ratiopharm | Dobutamin ratiopharm | Dobutamina Inibsa | Dobutamina Rovi | Posiject | Dobutamine Hydrobromide | Hydrobromide, Dobutamine | Dobutamine Hydrochloride | Hydrochloride, Dobutamine | Dobutamine Lactobionate | Lactobionate, Dobutamine | Dobutamine Tartrate | Tartrate, Dobutamine | Dobutamine Tartrate (1:1), (S-(R*,R*))-Isomer | Dobutamine Tartrate (1:1), (R-(R*,R*))-Isomer | Dobutamine, (-)-Isomer | Dobutamine, Phosphate (1:1) Salt (+)-Isomer | Dobutrex | Lilly 81929 | Oxiken | Dobutamine Phosphate (1:1) Salt, (-)-Isomer | Dobutamine (+)-Isomer
Chemical Information
Molecular Formula C18H24ClNO3
CAS Registry Number 49745-95-1
SMILES CC(CCC1=CC=C(C=C1)O)NCCC2=CC(=C(C=C2)O)O.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Angina pectoris02.02.02.002; 24.04.04.002--
Blood potassium decreased13.11.01.010--Not Available
Blood pressure abnormal13.14.03.001--Not Available
Blood pressure decreased13.14.03.002--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Dyspnoea02.11.05.003; 22.02.01.004--
Headache17.14.01.001--
Heart rate increased13.14.04.002--Not Available
Hypotension24.06.03.002--
Nausea07.01.07.001--
Palpitations02.11.04.012--
Phlebitis24.12.03.004; 12.02.01.002--
Skin necrosis23.03.03.011--Not Available
Thrombocytopenia01.08.01.002--Not Available
Ventricular extrasystoles02.03.04.007--Not Available
Inflammation10.02.01.089; 08.01.05.007--Not Available
Blood pressure measurement13.14.03.022--Not Available
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