Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Doxapram hydrochloride
Drug ID BADD_D00717
Description A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Indications and Usage For use as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.
Marketing Status approved; vet_approved
ATC Code R07AB01
DrugBank ID DB00561
KEGG ID D01872
MeSH ID D004315
PubChem ID 64647
TTD Drug ID D0M7BT
NDC Product Code 51662-1404; 0641-6018
UNII P5RU6UOQ5Y
Synonyms Doxapram | Dopram | Doxapram Hydrochloride | Hydrochloride, Doxapram | Docatone
Chemical Information
Molecular Formula C24H31ClN2O2
CAS Registry Number 113-07-5
SMILES CCN1CC(C(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3)CCN4CCOCC4.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Albuminuria20.02.01.001--Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Blood pressure increased13.14.03.005--Not Available
Blood urea increased13.13.01.006--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.009--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Clonus17.02.05.002--Not Available
Cough22.02.03.001--
Defaecation urgency07.02.04.001--Not Available
Diarrhoea07.02.01.001--
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.11.04.006--
Dyskinesia17.01.02.006--
Dyspnoea02.11.05.003; 22.02.01.004--
Electrocardiogram T wave amplitude decreased13.14.05.006--Not Available
Extensor plantar response17.02.01.005--Not Available
Feeling hot08.01.09.009--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Haematocrit13.01.05.017--Not Available
Haemoglobin decreased13.01.05.003--Not Available
Haemolysis01.06.04.002--
Hallucination19.10.04.003--
Headache17.14.01.001--
Heart rate abnormal13.14.04.006--Not Available
Hiccups22.12.01.001; 07.01.06.009--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperreflexia17.02.01.002--Not Available
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