| Pharmaceutical Information |
| Drug Name |
Doxercalciferol |
| Drug ID |
BADD_D00722 |
| Description |
Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 chronic kidney disease. Doxercalciferol is marketed under the brand name Hectoral by Genzyme Corporation, and is manufactured by Catalent Pharma Solutions, Inc. |
| Indications and Usage |
Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 chronic kidney disease. |
| Marketing Status |
approved |
| ATC Code |
H05BX03 |
| DrugBank ID |
DB06410
|
| KEGG ID |
D01009
|
| MeSH ID |
C042533
|
| PubChem ID |
5281107
|
| TTD Drug ID |
D0G5CF
|
| NDC Product Code |
11014-0030; 14474-023; 63415-0040; 62135-452; 64980-229; 70121-1393; 11014-0028; 58468-0127; 64980-228; 11014-0029; 71288-802; 55150-358; 62135-451; 64980-230; 54239-010; 43598-850; 58468-0123; 70121-1392; 62332-690; 68180-718; 66499-0011; 23155-540; 0409-1330; 0641-6154; 55150-359; 23155-538; 23155-539; 55150-357; 62135-450; 70121-1408 |
| UNII |
3DIZ9LF5Y9
|
| Synonyms |
1 alpha-hydroxyergocalciferol | 1alpha-hydroxyvitamin D2 | doxacalciferol | doxercalciferol | 1alpha(OH)2D2 | 1alpha-OHD2 | Hectorol |
|
| Chemical Information |
| Molecular Formula |
C28H44O2 |
| CAS Registry Number |
54573-75-0 |
| SMILES |
CC(C)C(C)C=CC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C |
| Chemical Structure |
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| ADRs Induced by Drug |
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