| Drug Name |
Esmolol hydrochloride |
| Drug ID |
BADD_D00814 |
| Description |
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate of heart contractions. Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. |
| Indications and Usage |
For the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other emergent circumstances where short term control of ventricular rate with a short-acting agent is desirable. Also used in noncompensatory sinus tachycardia where the rapid heart rate requires specific intervention. |
| Marketing Status |
approved |
| ATC Code |
C07AB09 |
| DrugBank ID |
DB00187
|
| KEGG ID |
D00644
|
| MeSH ID |
C036604
|
| PubChem ID |
104769
|
| TTD Drug ID |
D03XTC
|
| NDC Product Code |
10019-672; 25021-308; 63323-652; 10019-670; 44567-812; 51662-1322; 55150-194; 10019-075; 10019-666; 44567-450; 44567-451; 71872-7136; 10019-055; 51662-1371; 51662-1427; 0404-9825; 11712-260; 10019-115; 71872-7049; 10019-668; 62009-1905; 0404-9858; 67457-182; 14501-0075; 25021-309; 68083-211; 44567-811; 51662-1444; 10019-120; 63660-0004; 52584-194 |
| UNII |
V05260LC8D
|
| Synonyms |
esmolol | Brevibloc | esmolol hydrochloride | ASL 8052 | ASL-8052 |
