| Pharmaceutical Information |
| Drug Name |
Estrone |
| Drug ID |
BADD_D00834 |
| Description |
Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione. Estrone may be further metabolized to 16-alpha-hydroxyestrone, which may be reduced to estriol by estradiol dehydrogenase. |
| Indications and Usage |
For management of perimenopausal and postmenopausal symptoms. |
| Marketing Status |
approved |
| ATC Code |
G03CA07; G03CC04 |
| DrugBank ID |
DB00655
|
| KEGG ID |
D00067
|
| MeSH ID |
D004970
|
| PubChem ID |
5870
|
| TTD Drug ID |
D00ZFP
|
| NDC Product Code |
49452-2795; 0220-2129; 71052-548; 0220-2116; 44132-011; 51927-1709; 44132-003; 63083-1516; 38779-0891; 22552-0022; 51552-0445; 0220-2117 |
| UNII |
2DI9HA706A
|
| Synonyms |
Estrone | Estrone, (8 alpha)-Isomer | Estrone, (9 beta)-Isomer | Wehgen | Folliculin (Hormone) | Kestrone | Unigen | Estrone, (+-)-Isomer | Estrovarin |
|
| Chemical Information |
| Molecular Formula |
C18H22O2 |
| CAS Registry Number |
53-16-7 |
| SMILES |
CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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