Drug Name |
Ethinyl estradiol |
Drug ID |
BADD_D00844 |
Description |
Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering.[A191107] It was developed in an effort to create an estrogen with greater oral bioavailability.[A191107] These properties were achieved by the substitution of an ethinyl group at carbon 17 of [estradiol].[A191107] Ethinylestradiol soon replaced [mestranol] in contraceptive pills.[A191107]
Ethinylestradiol was granted FDA approval on 25 June 1943.[L11884] |
Indications and Usage |
Ethinylestradiol is combined with other drugs for use as a contraceptive, premenstrual dysphoric disorder, moderate acne, moderate to severe vasomotor symptoms of menopause, prevention of postmenopausal osteoporosis.[L11944,L11965,L11947,L11950,L11845,L9806,L11953,L10304,L11956,L11959,L11962] |
Marketing Status |
approved |
ATC Code |
Not Available |
DrugBank ID |
DB00977
|
KEGG ID |
D00554
|
MeSH ID |
D004997
|
PubChem ID |
5991
|
TTD Drug ID |
D06NXY
|
NDC Product Code |
63190-0620; 44132-010; 65089-0044; 12860-0463; 22552-0034; 44132-002; 60870-0463 |
UNII |
423D2T571U
|
Synonyms |
Ethinyl Estradiol | Estradiol, Ethinyl | Ethynyl Estradiol | Estradiol, Ethynyl | Ethinyloestradiol | 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)- | Ethinyl Estradiol Hemihydrate | Hemihydrate, Ethinyl Estradiol | Ethinyl Estradiol, (8 alpha)-Isomer | Ethinyl Estradiol, (8 alpha,17 alpha)-Isomer | Ethinyl Estradiol, (8 alpha,9 beta,13 alpha,14 beta)-Isomer | Progynon C | Microfollin | Microfollin Forte | Ethinyl-Oestradiol Effik | Ethinyl Oestradiol Effik | Ethinylestradiol Jenapharm | Jenapharm, Ethinylestradiol | Lynoral | Estinyl | Ethinyl Estradiol, (9 beta,17 alpha)-Isomer |