Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage Etonogestrel is administered in subdermal implants as long-acting reversible contraception. It is known to be effective in postpartum insertion including breastfeeding women.[A175990] Etonogestrel is part of the long-acting contraceptive implants that prevent pregnancy. The implant's effect can remain for 5 years.[L5698]
Marketing Status approved; investigational
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 64918-1500; 78206-145; 71161-147; 63190-0260; 45541-1192; 60870-0475; 63190-0480; 64918-1906; 65089-0053
UNII 304GTH6RNH
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Breast mass21.05.04.0020.003033%Not Available
Breast pain21.05.05.0030.022944%
Breast swelling21.05.05.0080.002750%Not Available
Breast tenderness21.05.05.0040.021604%Not Available
Chloasma18.08.02.002; 23.05.01.001--Not Available
Constipation07.02.02.001--
Cough22.02.03.001--
Crying08.01.03.005; 19.04.02.002; 17.02.05.013; 12.02.11.0010.008698%Not Available
Cyst16.02.02.002; 08.03.05.0010.002116%Not Available
Death neonatal18.04.01.002; 08.04.01.0020.000235%
Depressed mood19.15.02.0010.016644%Not Available
Depression19.15.01.0010.064929%
Depression suicidal19.15.01.0040.000235%Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis allergic23.03.04.003; 10.01.03.0140.001622%Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.0030.065211%Not Available
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.007--
Dysmenorrhoea21.01.01.0020.050424%
Dyspareunia21.03.02.016; 19.08.05.0040.002233%
Dyspepsia07.01.02.001--
Dysuria20.02.02.002--
Ectopic pregnancy18.02.02.0020.002586%Not Available
Emotional disorder19.04.02.0050.017772%Not Available
Endometriosis21.07.01.0040.003432%Not Available
Erythema23.03.06.001--Not Available
Erythema nodosum23.07.02.001; 10.02.01.0200.000799%Not Available
Facial pain08.01.08.0120.001599%
Fat tissue increased08.01.03.0090.002233%Not Available
Fatigue08.01.01.002--
The 2th Page    First    Pre   2 3 4 5 6    Next   Last    Total 14 Pages