Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Fenoldopam
Drug ID BADD_D00875
Description A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Indications and Usage For the in-hospital, short-term (up to 48 hours) management of severe hypertension when rapid, but quickly reversible, emergency reduction of blood pressure is clinically indicated, including malignant hypertension with deteriorating end-organ function.
Marketing Status approved
ATC Code C01CA19
DrugBank ID DB00800
KEGG ID D07946
MeSH ID D018818
PubChem ID 3341
TTD Drug ID D0R6BI
NDC Product Code Not Available
UNII INU8H2KAWG
Synonyms Fenoldopam | Fenoldopam Hydrobromide | Hydrobromide, Fenoldopam | SK&F-82526 | SK&F 82526 | SK&F82526 | SKF-82526 | SKF 82526 | SKF82526 | SKF-82526J | SKF 82526J | SKF82526J | SK&F-82526J | SK&F 82526J | SK&F82526J | Corlopam | Fenoldopam Mesylate
Chemical Information
Molecular Formula C16H16ClNO3
CAS Registry Number 67227-56-9
SMILES C1CNCC(C2=CC(=C(C(=C21)Cl)O)O)C3=CC=C(C=C3)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Angina pectoris24.04.04.002; 02.02.02.002--
Anxiety19.06.02.002--
Back pain15.03.04.005--
Blood creatinine increased13.13.01.004--
Blood lactate dehydrogenase increased13.04.02.002--
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Cardiac failure02.05.01.001--
Chest pain08.01.08.002; 02.02.02.011; 22.12.02.003--Not Available
Constipation07.02.02.001--
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dyspnoea02.11.05.003; 22.02.01.004--
Electrocardiogram T wave inversion13.14.05.007--Not Available
Extrasystoles02.03.02.003--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gastrointestinal pain07.01.05.005--
Haemoglobin13.01.05.018--Not Available
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypokalaemia14.05.03.002--
Hypotension24.06.03.002--
Injection site reaction12.07.03.015; 08.02.03.014--
Insomnia19.02.01.002; 17.15.03.002--
Leukocytosis01.02.01.002--
Muscle spasms15.05.03.004--
Myocardial infarction24.04.04.009; 02.02.02.007--
Myocardial ischaemia24.04.04.010; 02.02.02.008--Not Available
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