| Drug Name |
Fingolimod hydrochloride |
| Drug ID |
BADD_D00899 |
| Description |
Multiple sclerosis or MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects.[A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010.[L12651]
Fingolimod is currently being studied for the treatment of COVID-19, the disease caused by infection with the SARS-CoV-2 virus. Phase 2 clinical trials are currently underway and completion is expected in July 2020.[L12654] |
| Indications and Usage |
Fingolimod is indicated for the treatment of patients aged 10 and above with relapsing forms of multiple sclerosis, which may include clinically isolated syndrome, relapsing-remitting disease, as well as active secondary progressive disease.[L12651]
This drug is being studied for administration in patients infected with COVID-19 with a high risk for acute respiratory distress syndrome, or ARDS.[L12654] As of April 3 2020, this is currently not an approved indication and clinical trials are underway.[L12657] |
| Marketing Status |
approved; investigational |
| ATC Code |
L04AA27 |
| DrugBank ID |
DB08868
|
| KEGG ID |
D04187
|
| MeSH ID |
D000068876
|
| PubChem ID |
107969
|
| TTD Drug ID |
D0HI1K
|
| NDC Product Code |
57741-3100; 16729-342; 67877-476; 54893-0025; 65015-834; 69037-0006; 65035-138; 66039-886; 82920-019; 65727-036; 82245-0106 |
| UNII |
G926EC510T
|
| Synonyms |
Fingolimod Hydrochloride | 2-Amino-2-(2-(4-octylphenyl)ethyl)-1,3-propanediol hydrochloride | FTY-720 | FTY 720 | FTY720 | Gilenya | Gilenia | Fingolimod |
