Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Flavoxate hydrochloride
Drug ID BADD_D00901
Description A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Indications and Usage For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
Marketing Status approved
ATC Code G04BD02
DrugBank ID DB01148
KEGG ID D00718
MeSH ID D005422
PubChem ID 441345
TTD Drug ID D0ND2J
NDC Product Code 42806-058; 24658-720; 65129-1015; 0574-0115
UNII 9C05J6089W
Synonyms Flavoxate | Flavoxate Hydrochloride | Hydrochloride, Flavoxate | Urispas | Uronid | Bladuril | Spasuret
Chemical Information
Molecular Formula C24H26ClNO4
CAS Registry Number 3717-88-2
SMILES CC1=C(OC2=C(C1=O)C=CC=C2C(=O)OCCN3CCCCC3)C4=CC=CC=C4.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Confusional state17.02.03.005; 19.13.01.001--
Dry mouth07.06.01.002--
Dysuria20.02.02.002--
Eosinophilia01.02.04.001--
Eye disorder06.08.03.001--Not Available
Headache17.14.01.001--
Hyperpyrexia08.05.02.002--Not Available
Intraocular pressure increased13.07.04.002--Not Available
Leukopenia01.02.02.001--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Palpitations02.11.04.012--
Somnolence19.02.05.003; 17.02.04.006--
Tachycardia02.03.02.007--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Dermatosis23.03.03.017--Not Available
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