| Pharmaceutical Information |
| Drug Name |
Flecainide |
| Drug ID |
BADD_D00902 |
| Description |
Flecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone].[A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics.[A186931] It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.[L8878,L5056]
Flecainide was granted FDA approval on 31 October 1985.[L8875] |
| Indications and Usage |
In New Zealand and America, flecainide is indicated to prevent supraventricular arrhythmias and ventricular arrhythmias.[L8878] In the United States, it is also indicated to prevent paroxysmal atrial fibrillation and flutter.[A186886,L5056] |
| Marketing Status |
approved; withdrawn |
| ATC Code |
C01BC04 |
| DrugBank ID |
DB01195
|
| KEGG ID |
D07962
|
| MeSH ID |
D005424
|
| PubChem ID |
3356
|
| TTD Drug ID |
D03DAP
|
| NDC Product Code |
Not Available |
| UNII |
K94FTS1806
|
| Synonyms |
Flecainide | Flecainide Acetate | Flecainide Monoacetate | Flecainide Monoacetate, (R)-Isomer | Flecainide Monoacetate, (S)-Isomer | Flecainide, (R)-Isomer | Flecainide, (S)-Isomer | Flecainide, 5-HO-N-(6-oxo)-Derivative | Flecainide, 5-HO-N-(6-oxo)-Derivative, (+-)-Isomer | Flecatab | R818 | Tambocor | Flecadura | Flecainide Monoacetate, (+-)-Isomer | Flecainid-Isis | Flecainid Isis | Flécaïne | Apocard |
|
| Chemical Information |
| Molecular Formula |
C17H20F6N2O3 |
| CAS Registry Number |
54143-55-4 |
| SMILES |
C1CCNC(C1)CNC(=O)C2=C(C=CC(=C2)OCC(F)(F)F)OCC(F)(F)F |
| Chemical Structure |
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| ADRs Induced by Drug |
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