Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Flucloxacillin
Drug ID BADD_D00911
Description Antibiotic analog of [cloxacillin].
Indications and Usage Used to treat bacterial infection by susceptible microorganisms.
Marketing Status approved; investigational
ATC Code J01CF05
DrugBank ID DB00301
KEGG ID D04196
MeSH ID D005436
PubChem ID 21319
TTD Drug ID D0Q2AT
NDC Product Code Not Available
UNII 43B2M34G2V
Synonyms Floxacillin | Fluorochloroxacillin | Flucloxacillin
Chemical Information
Molecular Formula C19H17ClFN3O5S
CAS Registry Number 5250-39-5
SMILES CC1=C(C(=NO1)C2=C(C=CC=C2Cl)F)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Jaundice cholestatic09.01.01.005--Not Available
Malaise08.01.01.003--
Myalgia15.05.02.001--
Nausea07.01.07.001--
Nephritis20.05.02.001--Not Available
Nervous system disorder17.02.10.001--Not Available
Neutropenia01.02.03.004--Not Available
Pseudomembranous colitis11.02.02.002; 07.19.01.003--Not Available
Purpura01.01.04.003; 24.07.06.005; 23.06.01.004--
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Seizure17.12.03.001--
Serum sickness12.02.08.004; 10.01.03.004--
Skin disorder23.03.03.007--Not Available
Stevens-Johnson syndrome10.01.01.045; 23.03.01.007; 12.03.01.014; 11.07.01.005--
Thrombocytopenia01.08.01.002--Not Available
Thrombocytopenic purpura23.06.01.007; 01.08.01.003--Not Available
Toxic epidermal necrolysis10.01.01.006; 23.03.01.008; 12.03.01.015; 11.07.01.006--
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vascular purpura23.06.01.008; 24.07.06.011; 01.01.04.007--Not Available
Vomiting07.01.07.003--
Tubulointerstitial nephritis20.05.02.002--Not Available
Lymphatic disorder01.09.01.003--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Vulvovaginal pruritus23.03.12.009; 21.08.02.004--Not Available
Connective tissue disorder10.04.04.026; 15.06.01.006--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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