Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Flutamide
Drug ID BADD_D00943
Description An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Indications and Usage For the management of locally confined Stage B2-C and Stage D2 metastatic carcinoma of the prostate
Marketing Status approved; investigational
ATC Code L02BB01
DrugBank ID DB00499
KEGG ID D00586
MeSH ID D005485
PubChem ID 3397
TTD Drug ID D0Y0SW
NDC Product Code 69097-915; 80725-600; 44657-0048; 60429-272; 12780-4750; 44657-0056; 49884-753; 53104-7536
UNII 76W6J0943E
Synonyms Flutamide | Niftolid | Niftolide | Chimax | Cytamid | Eulexin | Euflex | Drogenil | Eulexine | Fluken | Flulem | Flumid | Fluta 1A Pharma | Fluta-cell | Fluta cell | Flutacell | Fluta-GRY | Fluta GRY | FlutaGRY | Flutamin | Flutandrona | Flutaplex | Flutexin | Fugerel | Grisetin | Novo-Flutamide | Novo Flutamide | NovoFlutamide | Oncosal | PMS-Flutamide | PMS Flutamide | Prostacur | Prostica | Prostogenat | SCH-13521 | SCH 13521 | SCH13521 | Testotard | Apimid | Apo-Flutamide | Apo Flutamide | ApoFlutamide
Chemical Information
Molecular Formula C11H11F3N2O3
CAS Registry Number 13311-84-7
SMILES CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Galactorrhoea05.03.04.002; 21.05.02.002--Not Available
Gynaecomastia21.05.04.003; 05.05.02.003--
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.006--
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Hepatic encephalopathy17.13.01.003; 09.01.03.006--Not Available
Hepatic necrosis09.01.07.002--
Hepatitis09.01.07.004--Not Available
Herpes zoster23.11.05.005; 17.09.03.026; 11.05.02.003--
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hypertension24.08.02.001--
Increased appetite08.01.09.027; 14.03.01.003--Not Available
Injection site irritation12.07.03.027; 08.02.03.027--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Interstitial lung disease22.01.02.003; 10.02.01.033--Not Available
Jaundice01.06.04.004; 23.03.03.030; 09.01.01.004--Not Available
Jaundice cholestatic09.01.01.005--Not Available
Laboratory test abnormal13.18.01.001--Not Available
Leukopenia01.02.02.001--Not Available
Libido decreased21.03.02.005; 19.08.03.001--
Loss of libido19.08.03.003--Not Available
Lung disorder22.02.07.001--Not Available
Malaise08.01.01.003--
Menopausal symptoms21.02.02.002--Not Available
Methaemoglobinaemia01.05.01.002--
Nausea07.01.07.001--
Neoplasm16.16.02.001--Not Available
Neoplasm malignant16.16.01.001--Not Available
Nervousness19.06.02.003--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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