Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Fosaprepitant
Drug ID BADD_D00962
Description Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Indications and Usage For the prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy.
Marketing Status approved
ATC Code Not Available
DrugBank ID DB06717
KEGG ID D10895
MeSH ID C579707
PubChem ID 135413538
TTD Drug ID Not Available
NDC Product Code 43598-948; 72205-054; 72205-083; 16714-929; 68180-690; 43598-859; 71839-104; 63323-972; 70710-1615; 16729-240; 68001-517; 0781-3497; 68001-421; 16714-120; 69539-181; 72205-026; 60505-6105; 69097-830; 69539-034; 67457-889; 0591-4385
UNII 6L8OF9XRDC
Synonyms fosaprepitant | Emend for injection | fosaprepitant dimeglumine | L 785,298 | L785,298 | L-785,298
Chemical Information
Molecular Formula C23H22F7N4O6P
CAS Registry Number 172673-20-0
SMILES CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NN(C(=O)N3)P(=O)(O)O)C4=CC=C( C=C4)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ear disorder04.03.01.001--Not Available
Eructation07.01.02.003--
Erythema23.03.06.001--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Euphoric mood19.04.02.006--
Eye disorder06.08.03.001--Not Available
Faeces hard07.01.03.003--Not Available
Fatigue08.01.01.002--
Febrile neutropenia08.05.02.004; 01.02.03.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gait disturbance15.03.05.013; 17.02.05.016; 08.01.02.002--
Gastrooesophageal reflux disease07.02.02.003--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Glycosuria20.02.01.005--
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.006--
Blood urine present13.13.02.002--Not Available
Headache17.14.01.001--
Hiccups22.12.01.001; 07.01.06.009--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
Hyponatraemia14.05.04.002--
Immune system disorder10.02.01.001--Not Available
Infection11.01.08.002--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
Malaise08.01.01.003--
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