Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fosinoprilat
Drug ID BADD_D00969
Description Fosinoprilat is the active phosphinic acid metabolite of prodrug [fosinopril], which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
Indications and Usage Not Available
Marketing Status experimental
ATC Code Not Available
DrugBank ID DB14207
KEGG ID D03772
MeSH ID C046965
PubChem ID 62956
TTD Drug ID Not Available
NDC Product Code Not Available
UNII S312EY6ZT8
Synonyms fosinoprilat | fosinoprilic acid | fosfenopril | SQ 27519 | SQ-27519 | SQ-27,519
Chemical Information
Molecular Formula C23H34NO5P
CAS Registry Number 95399-71-6
SMILES C1CCC(CC1)C2CC(N(C2)C(=O)CP(=O)(CCCCC3=CC=CC=C3)O)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Drug interaction08.06.03.001--Not Available
Dry mouth07.06.01.002--
Dysgeusia07.14.03.001; 17.02.07.003--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dysphonia19.19.03.002; 17.02.08.004; 22.12.03.006--
Dyspnoea02.11.05.003; 22.02.01.004--
Eczema23.03.04.0060.007032%
Eosinophilia01.02.04.001--
Epistaxis24.07.01.005; 22.04.03.001--
Eye irritation06.04.05.003--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.0030.007032%
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Feeling cold08.01.09.008--Not Available
Flatulence07.01.04.002--
Flushing08.01.03.025; 24.03.01.002; 23.06.05.003--
Gastrointestinal pain07.01.05.005--
Gout15.01.06.001; 14.09.01.001--Not Available
Head discomfort17.02.05.0270.015471%Not Available
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hepatitis09.01.07.004--Not Available
Hepatocellular injury09.01.07.0080.010549%Not Available
Hepatomegaly09.01.05.001--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperkalaemia14.05.03.001--
Hypertension24.08.02.0010.007032%
Hypertensive crisis24.08.01.001--Not Available
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
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