Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Frovatriptan succinate
Drug ID BADD_D00977
Description Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Indications and Usage For the acute treatment of migraine attacks with or without aura in adults.
Marketing Status approved; investigational
ATC Code N02CC07
DrugBank ID DB00998
KEGG ID D04264
MeSH ID C108128
PubChem ID 152943
TTD Drug ID D06FPQ
NDC Product Code 68462-694; 0603-3718; 66039-865; 50742-299; 69238-1539; 82245-0110; 68625-025; 76055-0008; 63481-025
UNII D28J6W18HY
Synonyms frovatriptan | 3-methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole | Frova | VML-251 | VML251 | Frovelan | SB 209509 | Allegro | frovatriptan succinate | (+)-(R)-5,6,7,8-tetrahydro-6-(methylamino)carbazole-3-carboxamide succinate (1:1), monohydrate
Chemical Information
Molecular Formula C18H25N3O6
CAS Registry Number 158930-17-7
SMILES CNC1CCC2=C(C1)C3=C(N2)C=CC(=C3)C(=O)N.C(CC(=O)O)C(=O)O.O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Migraine24.03.05.003; 17.14.02.001--Not Available
Muscle contractions involuntary17.05.03.001; 15.05.03.008--Not Available
Muscle spasms15.05.03.004--
Muscular weakness15.05.06.001; 17.05.03.005--
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Myocardial ischaemia24.04.04.010; 02.02.02.008--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Nocturia20.02.03.001--Not Available
Oedema mouth23.04.01.008; 10.01.05.006; 07.05.04.001--Not Available
Oesophageal spasm07.02.04.004--Not Available
Osteoarthritis15.01.04.001--Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Palpitations02.11.04.012--
Paraesthesia17.02.06.005; 23.03.03.094--
Peptic ulcer07.04.07.001--Not Available
Personality disorder19.05.02.002--Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pollakiuria20.02.02.007--
Polyuria20.02.03.002--Not Available
Pruritus23.03.12.001--
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Reflexes abnormal17.02.01.006--Not Available
Renal pain20.02.03.003--Not Available
Rhinitis11.01.13.004; 22.07.03.006--
Salivary gland pain07.06.02.002--Not Available
Salivary hypersecretion07.06.01.009--Not Available
The 3th Page    First    Pre   3 4    Next   Last    Total 4 Pages