Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Gadodiamide
Drug ID BADD_D00985
Description Gadodiamide is a paramagnetic gadolinium-based contrast agent (GBCA) that is used in MR imaging procedures to assist in the visualization of blood vessels. It is intravenously injected and is commonly marketed under the trade name Omniscan.
Indications and Usage For intravenous use in MRI to visualize lesions with abnormal vascularity (or those thought to cause abnormalities in the blood-brain barrier) in the brain (intracranial lesions), spine, and associated tissues.
Marketing Status approved; investigational
ATC Code V08CA03
DrugBank ID DB00225
KEGG ID D04284
MeSH ID C064925
PubChem ID 60754
TTD Drug ID D03EEH
NDC Product Code 0407-0691; 0407-0690; 71806-069
UNII 84F6U3J2R6
Synonyms gadodiamide | Gd-DTPA bis-(methylamide) | Gd-DTPA-BMA | Omniscan | Omniscan Unique Softpack
Chemical Information
Molecular Formula C16H28GdN5O9
CAS Registry Number 122795-43-1
SMILES CNC(=O)CN(CCN(CCN(CC(=O)NC)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].O.[Gd+3]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Ageusia17.02.07.001; 07.14.03.003--Not Available
Amnesia19.20.01.001; 17.03.02.0010.021340%
Anaphylactic reaction24.06.03.006; 10.01.07.0010.014227%
Anaphylactic shock24.06.02.004; 10.01.07.0020.028454%Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.0030.007113%Not Available
Anxiety19.06.02.0020.053350%
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.0010.053350%
Asthenia08.01.01.0010.042680%Not Available
Ataxia17.02.02.001; 08.01.02.004--
Back pain15.03.04.0050.033433%
Blister12.01.06.002; 23.03.01.0010.014227%Not Available
Bone pain15.02.01.0010.017783%
Burning sensation17.02.06.001; 08.01.09.0290.045526%Not Available
Cardiac failure02.05.01.001--
Cardio-respiratory arrest02.03.04.002; 22.02.06.0070.010670%Not Available
Chest discomfort02.02.02.009; 22.12.02.002; 08.01.08.0190.028454%Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.0010.040546%
Chromaturia20.02.01.0020.007113%
Cold sweat23.02.03.002; 08.01.03.0240.034856%Not Available
Coma17.02.09.001--Not Available
Confusional state19.13.01.001; 17.02.03.0050.024897%
Contrast media reaction12.02.05.029; 10.01.01.0110.026320%Not Available
Coordination abnormal17.02.02.004--Not Available
Cough22.02.03.0010.117371%
Death08.04.01.001--
Diarrhoea07.02.01.001--
Discomfort08.01.08.0030.007113%Not Available
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