Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Gadofosveset trisodium
Drug ID BADD_D00988
Description Gadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels. The agent allows for the vascular system to be imaged more clearly by the MRA. In this way, gadofosveset trisodium is used to help diagnose certain disorders of the heart and blood vessels.
Indications and Usage Gadofosveset trisodium is indicated for use as a contrast agent in magnetic resonance angiography (MRA) to evaluate aortoiliac occlusive disease (AIOD) in adults with known or suspected peripheral vascular disease.
Marketing Status approved
ATC Code V08CA11
DrugBank ID DB06705
KEGG ID D04286
MeSH ID C109932
PubChem ID 73049652
TTD Drug ID D0H0WK
NDC Product Code Not Available
UNII XM33Q67UVH
Synonyms gadofosveset trisodium | gadofosveset | MS 325 | MS-325 | Vasovist
Chemical Information
Molecular Formula C33H38GdN3Na3O14P
CAS Registry Number 193901-90-5
SMILES C1CC(CCC1OP(=O)([O-])OCC(CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC (=O)[O-])(C2=CC=CC=C2)C3=CC=CC=C3.[Na+].[Na+].[Na+].[Gd+3]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.007--
Dysgeusia17.02.07.003; 07.14.03.001--
Feeling cold08.01.09.008--Not Available
Headache17.14.01.001--
Hypertension24.08.02.001--
Injection site bruising08.02.03.042; 24.07.06.017; 23.03.11.015; 12.07.03.042--Not Available
Nausea07.01.07.001--
Paraesthesia23.03.03.094; 17.02.06.005--
Pruritus23.03.12.001--
Vasodilatation23.06.05.006; 24.03.02.003--Not Available
Vessel puncture site bruise24.07.06.016; 23.03.11.014; 12.07.04.009; 08.02.04.009--Not Available
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