| Pharmaceutical Information |
| Drug Name |
Gadoxetate disodium |
| Drug ID |
BADD_D00995 |
| Description |
Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. It is marketed by Bayer HealthCare Pharmaceuticals and FDA approved on July 3, 2008. |
| Indications and Usage |
Gadoxetate is used as a contrast medium for magnetic resonance imaging (MRI) to detect and characterize lesions in the liver. |
| Marketing Status |
approved |
| ATC Code |
V08CA10 |
| DrugBank ID |
DB08884
|
| KEGG ID |
D04288
|
| MeSH ID |
C073590
|
| PubChem ID |
9961939
|
| TTD Drug ID |
D0X2FT
|
| NDC Product Code |
61662-0020; 50419-320 |
| UNII |
HOY74VZE0M
|
| Synonyms |
gadolinium ethoxybenzyl DTPA | Gd-EOB-DTPA | gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid | gadoxetic acid | gadoxetic acid disodium | gadoxetate disodium | disodium gadoxetate | gadolinium (4S)-4-(4-ethoxybenzyl)-3,6,9-tris(carboxylatomethyl)-3,6,9-triazaundecanoic acid disodium salt | Eovist | Primovist |
|
| Chemical Information |
| Molecular Formula |
C23H28GdN3Na2O11 |
| CAS Registry Number |
135326-22-6 |
| SMILES |
CCOC1=CC=C(C=C1)CC(CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O
-].[Na+].[Na+].[Gd+3] |
| Chemical Structure |
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| ADRs Induced by Drug |
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