Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ganciclovir sodium
Drug ID BADD_D01004
Description An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Indications and Usage For induction and maintenance in the treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). Also used in the treatment of severe cytomegalovirus (CMV) disease, including CMV pneumonia, CMV gastrointestinal disease, and disseminated CMV infections, in immunocompromised patients.
Marketing Status approved; investigational
ATC Code S01AD09; J05AB06
DrugBank ID DB01004
KEGG ID D04301
MeSH ID D015774
PubChem ID 23700083
TTD Drug ID D05ARP
NDC Product Code 46014-1054; 70436-089; 25021-185; 63323-315; 0143-9299; 51817-171; 0004-6941
UNII 02L083W284
Synonyms Ganciclovir | Gancyclovir | BW-759 | Ganciclovir Sodium | Ganciclovir, Monosodium Salt | RS-21592 | BIOLF-62 | Cytovene
Chemical Information
Molecular Formula C9H12N5NaO4
CAS Registry Number 84245-13-6
SMILES C1=NC2=C(N1COC(CO)CO)N=C(N=C2[O-])N.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Flatulence07.01.04.002--
Gastrointestinal perforation07.04.04.001--Not Available
Granulocytopenia01.02.03.003--Not Available
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.006--
Haemolytic anaemia01.06.03.002--Not Available
Haemolytic uraemic syndrome20.01.03.011; 01.06.02.001--
Hallucination19.10.04.003--
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hepatic function abnormal09.01.02.001--Not Available
Hepatitis09.01.07.004--Not Available
Hypercalcaemia05.04.01.002; 14.04.01.003--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
Hyponatraemia14.05.04.002--
Hypotension24.06.03.002--
IIIrd nerve paralysis17.04.02.003; 06.05.02.011--Not Available
Infection11.01.08.002--Not Available
Infertility21.03.02.001--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Injection site inflammation12.07.03.009; 08.02.03.008--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Intestinal ulcer07.04.06.003--Not Available
Intracranial pressure increased17.07.02.002--Not Available
Irritability19.04.02.013; 08.01.03.011--
Leukopenia01.02.02.001--Not Available
Macular oedema06.04.06.005--Not Available
Malaise08.01.01.003--
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