| Pharmaceutical Information |
| Drug Name |
Glucagon monohydrochloride |
| Drug ID |
BADD_D01027 |
| Description |
Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643]
Glucagon was granted FDA approval on 14 November 1960.[L7631] |
| Indications and Usage |
Glucagon is indicated as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] |
| Marketing Status |
approved |
| ATC Code |
H04AA01 |
| DrugBank ID |
DB00040
|
| KEGG ID |
D02118
|
| MeSH ID |
D005934
|
| PubChem ID |
16186213
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
0002-7529; 43742-0734; 63323-594; 51662-1498; 0002-6145; 63323-582; 63323-593; 63323-596; 0002-8031; 66558-0195; 41524-0005; 0548-5850; 55463-0009; 63083-1555; 50090-6550 |
| UNII |
76LA80IG2G
|
| Synonyms |
Glucagon | Proglucagon (33-61) | HG-Factor | HG Factor | Glukagon | Glucagon (1-29) | Hyperglycemic-Glycogenolytic Factor | Hyperglycemic Glycogenolytic Factor |
|
| Chemical Information |
| Molecular Formula |
C153H226ClN43O49S |
| CAS Registry Number |
19179-82-9 |
| SMILES |
CC(C)CC(C(=O)NC(CCSC)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC
=C21)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)C)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CC(=O)O)NC(=O)C
(CCC(=O)N)NC(=O)C(C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(
=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC5
=CC=C(C=C5)O)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC6=CC=CC=C6)NC(=O
)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CC7=CN=CN7)N.Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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