| Pharmaceutical Information |
| Drug Name |
Glycerol phenylbutyrate |
| Drug ID |
BADD_D01032 |
| Description |
Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013. |
| Indications and Usage |
Glycerol phenylbutyrate is a nitrogen-binding agent for the chronic management of adult and pediatric patients ≥2 years of age with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone. |
| Marketing Status |
approved |
| ATC Code |
A16AX09 |
| DrugBank ID |
DB08909
|
| KEGG ID |
D10127
|
| MeSH ID |
C570223
|
| PubChem ID |
10482134
|
| TTD Drug ID |
D0E0BD
|
| NDC Product Code |
75987-050; 14501-0097; 58159-034; 67262-0008; 45941-3054; 65977-0121; 67262-0009 |
| UNII |
ZH6F1VCV7B
|
| Synonyms |
glycerol phenylbutyrate | HPN 100 | HPN100 | HPN-100 | Ravicti |
|
| Chemical Information |
| Molecular Formula |
C33H38O6 |
| CAS Registry Number |
611168-24-2 |
| SMILES |
C1=CC=C(C=C1)CCCC(=O)OCC(COC(=O)CCCC2=CC=CC=C2)OC(=O)CCCC3=CC=CC=C3 |
| Chemical Structure |
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| ADRs Induced by Drug |
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