Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Gonadorelin
Drug ID BADD_D01036
Description Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.
Indications and Usage For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.
Marketing Status approved; investigational; vet_approved
ATC Code H01CA01; V04CM01
DrugBank ID DB00644
KEGG ID D08027
MeSH ID D007987
PubChem ID 638793
TTD Drug ID D04ODH
NDC Product Code 55463-0016
UNII 9O7312W37G
Synonyms Gonadotropin-Releasing Hormone | Gonadotropin Releasing Hormone | Gn-RH | Gonadoliberin | LHFSH Releasing Hormone | Releasing Hormone, LHFSH | LH-RH | LFRH | LH-Releasing Hormone | LH Releasing Hormone | LH-FSH Releasing Hormone | LH FSH Releasing Hormone | LHFSHRH | LHRH | Luliberin | Gonadorelin | Luteinizing Hormone-Releasing Hormone | Luteinizing Hormone Releasing Hormone | FSH-Releasing Hormone | FSH Releasing Hormone | GnRH | Factrel | Cystorelin | Gonadorelin Hydrochloride | Kryptocur | Dirigestran | Gonadorelin Acetate
Chemical Information
Molecular Formula C55H75N17O13
CAS Registry Number 9034-40-6
SMILES CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)CNC(=O)C(CC2=CC=C(C=C 2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pain08.01.08.004--
Pelvic pain21.10.01.001; 20.02.03.007; 07.01.06.012--
Premature labour18.07.01.002--Not Available
Pruritus23.03.12.001--
Puerperal pyrexia18.06.01.003; 11.01.10.009; 08.05.02.006--Not Available
Shock24.06.02.002--Not Available
Swelling08.01.03.015--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Vomiting07.01.07.003--
Contusion15.03.05.007; 24.07.06.001; 23.03.11.002; 12.01.06.001--
Angiopathy24.03.02.007--Not Available
Secondary hypogonadism21.16.01.001; 05.03.04.008--Not Available
Breast disorder21.05.04.004--Not Available
Embolism24.01.01.009--
Ovarian neoplasm21.11.01.005; 16.12.06.001--Not Available
Adnexal torsion21.11.02.012--Not Available
Haemoperitoneum24.07.02.065; 07.07.02.007; 12.01.17.007--Not Available
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