Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Guanidine hydrochloride
Drug ID BADD_D01049
Description A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
Indications and Usage For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis.
Marketing Status approved
ATC Code Not Available
DrugBank ID DB00536
KEGG ID D11626
MeSH ID D019791
PubChem ID 5742
TTD Drug ID D0F7NZ
NDC Product Code Not Available
UNII 3YQC9ZY4YB
Synonyms Guanidine | Guanidinium | Guanidine Monohydrate | Monohydrate, Guanidine | Guanidine Monohydrobromide | Monohydrobromide, Guanidine | Guanidine Monohydroiodine | Monohydroiodine, Guanidine | Guanidine Sulfite (1:1) | Guanidine Phosphate | Phosphate, Guanidine | Guanidine Sulfate | Sulfate, Guanidine | Guanidine Sulfate (1:1) | Guanidine Sulfate (2:1) | Guanidine Hydrochloride | Hydrochloride, Guanidine | Guanidinium Chloride | Chloride, Guanidinium | Guanidium Chloride | Chloride, Guanidium | Guanidine Monohydrochloride | Monohydrochloride, Guanidine | Guanidine Nitrate | Nitrate, Guanidine
Chemical Information
Molecular Formula CH6ClN3
CAS Registry Number 50-01-1
SMILES C(=N)(N)N.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rash23.03.13.001--Not Available
Rash macular23.03.13.003--Not Available
Renal tubular necrosis20.01.07.003--Not Available
Skin exfoliation23.03.07.003--Not Available
Tachycardia02.03.02.007--Not Available
Thrombocytopenia01.08.01.002--Not Available
Tremor17.01.06.002--
Tubulointerstitial nephritis20.05.02.002--Not Available
Affect lability19.04.01.001--Not Available
Decreased appetite08.01.09.028; 14.03.01.005--
Psychotic disorder19.03.01.002--
Oropharyngeal pain22.12.03.016; 07.05.05.004--
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