Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Halobetasol
Drug ID BADD_D01051
Description Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.[L15047]
Indications and Usage Ulobetasol cream and ointment are indicated in the treatment of inflammatory and pruritic corticosteroid responsive dermatoses.[L15047] Ulobetasol lotion is indicated in the treatment of plaque psoriasis.[L15052]
Marketing Status approved
ATC Code D07AC21
DrugBank ID DB00596
KEGG ID D08660
MeSH ID C064466
PubChem ID 5311167
TTD Drug ID D00XPC
NDC Product Code Not Available
UNII 9P6159HM7T
Synonyms halobetasol | ulobetasol | Ultravate | halobetasol propionate | 6 alpha-fluoroclobetasol 17-propionate | 6-fluoroclobetasol 17-propionate | CGP 14 458 | CGP-14458 | CGP 14458
Chemical Information
Molecular Formula C22H27ClF2O4
CAS Registry Number 98651-66-2
SMILES CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pain08.01.08.004--
Paraesthesia23.03.03.094; 17.02.06.005--
Parkinsonism17.01.05.003--Not Available
Photosensitivity reaction23.03.09.003--
Priapism24.04.12.007; 21.03.01.005--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rash macular23.03.13.003--Not Available
Rash pustular23.03.10.003; 11.01.12.002--
Red blood cell count decreased13.01.05.007--Not Available
Restlessness19.11.02.002; 17.02.05.021--
Retinopathy24.03.07.003; 06.10.02.001--
Salivary hypersecretion07.06.01.009--Not Available
Skin atrophy23.01.05.001--
Skin hypopigmentation23.05.02.003--
Skin striae23.01.05.002--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Tachycardia02.03.02.007--Not Available
Tardive dyskinesia17.01.02.012--Not Available
Telangiectasia24.03.03.003; 23.06.03.001--
Torsade de pointes02.03.04.005--Not Available
Urticaria10.01.06.001; 23.04.02.001--
Ventricular arrhythmia02.03.04.006--
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred17.17.01.010; 06.02.06.007--
Visual impairment06.02.10.013--Not Available
Vomiting07.01.07.003--
Lactation disorder21.05.02.004; 18.06.02.003--
Decreased appetite14.03.01.005; 08.01.09.028--
Erectile dysfunction21.03.01.007; 19.08.04.001--
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