Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Halothane
Drug ID BADD_D01057
Description A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
Indications and Usage For the induction and maintenance of general anesthesia
Marketing Status approved; vet_approved
ATC Code N01AB01
DrugBank ID DB01159
KEGG ID D00542
MeSH ID D006221
PubChem ID 3562
TTD Drug ID D0D8VE
NDC Product Code Not Available
UNII UQT9G45D1P
Synonyms Halothane | 1,1,1-Trifluoro-2-Chloro-2-Bromoethane | Ftorotan | Narcotan | Fluothane
Chemical Information
Molecular Formula F3CCHBrCl
CAS Registry Number 151-67-7
SMILES C(C(F)(F)F)(Cl)Br
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Arrhythmia02.03.02.001--Not Available
Cardiac arrest02.03.04.001--
Chills15.05.03.016; 08.01.09.001--
Chromaturia20.02.01.002--
Coagulopathy01.01.02.001--Not Available
Coma hepatic17.02.09.002; 09.01.03.005--Not Available
Enzyme abnormality14.11.01.015--Not Available
Eosinophilia01.02.04.001--
Hepatic failure09.01.03.002--
Hepatic function abnormal09.01.02.001--Not Available
Hepatic necrosis09.01.07.002--
Hepatitis09.01.07.004--Not Available
Hepatocellular injury09.01.07.008--Not Available
Hepatotoxicity12.03.01.008; 09.01.07.009--Not Available
Hyperbilirubinaemia14.11.01.010; 09.01.01.003; 01.06.04.003--Not Available
Hyperpyrexia08.05.02.002--Not Available
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Jaundice09.01.01.004; 23.03.03.030; 01.06.04.004--Not Available
Jaundice hepatocellular09.01.01.006--Not Available
Nausea07.01.07.001--
Pyrexia08.05.02.003--
Respiratory arrest22.02.01.009--Not Available
Vomiting07.01.07.003--
Decreased appetite14.03.01.005; 08.01.09.028--
Renal impairment20.01.03.010--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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