| Drug Name |
Hydralazine hydrochloride |
| Drug ID |
BADD_D01082 |
| Description |
Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed.[A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a first line therapy for these indications since the development of newer antihypertensive medications.[T691]
Hydralazine hydrochloride was FDA approved on 15 January 1953.[L8779] |
| Indications and Usage |
Hydralazine is indicated alone or adjunct to standard therapy to treat essential hypertension.[L8782] A combination product with isosorbide dinitrate is indicated as an adjunct therapy in the treatment of heart failure.[L8785] |
| Marketing Status |
approved |
| ATC Code |
C02DB02 |
| DrugBank ID |
DB01275
|
| KEGG ID |
D01302
|
| MeSH ID |
D006830
|
| PubChem ID |
9351
|
| TTD Drug ID |
D0K1XK
|
| NDC Product Code |
58032-1004; 68259-1313; 51079-076; 55150-400; 55154-5689; 67877-292; 71872-7268; 72241-004; 72241-006; 75834-127; 75834-128; 17478-934; 31722-520; 31722-522; 43353-124; 50090-4641; 63629-8493; 63629-8494; 71209-017; 72572-265; 31722-521; 50228-183; 50228-184; 51079-074; 55154-7294; 63629-8495; 63629-8496; 63739-327; 70518-2551; 71209-016; 72241-005; 55154-9554; 62584-734; 63187-901; 67877-290; 70934-764; 71872-7145; 75834-126; 68259-1307; 69037-0047; 23155-002; 50228-182; 51079-075; 51662-1388; 55154-7293; 55154-7295; 62135-582; 62584-733; 0404-9994; 70518-0666; 70518-0832; 70934-571; 71205-091; 71335-1589; 0615-7973; 71872-7274; 76282-312; 55512-0010; 39822-0500; 50090-0137; 50228-185; 62135-579; 63629-8757; 63739-328; 64380-736; 67877-291; 71205-072; 71335-0482; 71335-1236; 0641-6231; 76282-311; 77771-184; 77771-185; 0904-6442; 62350-0080; 77777-116; 23155-004; 50090-0139; 50111-327; 50111-398; 51662-1376; 55154-6628; 63323-614; 64380-733; 64380-734; 0517-0901; 70518-1685; 71610-562; 59651-148; 66039-957; 72643-001; 31722-519; 43353-205; 50111-328; 55154-2082; 63629-5246; 63629-8497; 68071-2530; 68788-8087; 70518-0637; 71209-018; 71335-1685; 71335-9722; 71610-549; 71610-561; 76282-310; 0904-6441; 17511-102; 55289-133; 62135-581; 64380-735; 67544-657; 71335-0594; 71872-7050; 77771-182; 0904-6440; 0904-6443; 49452-3544; 23155-001; 43063-392; 50111-397; 61919-312; 62135-580; 63629-5696; 67877-293; 0404-9986; 68071-5285; 68084-447; 71335-0202; 76282-309; 77771-183; 65691-0088; 68554-0023; 23155-003; 55154-2083; 55154-5085 |
| UNII |
FD171B778Y
|
| Synonyms |
Hydralazine | Hydrallazin | Hydrazinophthalazine | Apressin | Nepresol | Hydralazine mono-Hydrochloride | Hydralazine mono Hydrochloride | mono-Hydrochloride, Hydralazine | Apressoline | Apresoline | Hydralazine Hydrochloride | Hydrochloride, Hydralazine |
