Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Hydroxyproline
Drug ID BADD_D01108
Description Hydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products. Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis. Therapeutically, hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small, superficial wounds.
Indications and Usage Used in France as a combination product for the treatment of small, superficial wounds.
Marketing Status experimental
ATC Code Not Available
DrugBank ID DB08847
KEGG ID Not Available
MeSH ID D006909
PubChem ID 5810
TTD Drug ID Not Available
NDC Product Code Not Available
UNII RMB44WO89X
Synonyms Hydroxyproline | 4-Hydroxyproline | 4 Hydroxyproline | Oxyproline | cis-4-Hydroxyproline | cis 4 Hydroxyproline
Chemical Information
Molecular Formula C5H9NO3
CAS Registry Number 618-28-0
SMILES C1C(CNC1C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rash23.03.13.001--Not Available
Skin irritation23.03.04.009--Not Available
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