| Pharmaceutical Information |
| Drug Name |
Icodextrin |
| Drug ID |
BADD_D01124 |
| Description |
Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways. |
| Indications and Usage |
Used for continuous ambulatory peritoneal dialysis (CAPD) of diabetic patients or automated peritoneal dialysis (APD) for the management of end-stage renal disease. |
| Marketing Status |
approved; investigational |
| ATC Code |
Not Available |
| DrugBank ID |
DB00702
|
| KEGG ID |
D03266
|
| MeSH ID |
D000077607
|
| PubChem ID |
3517
|
| TTD Drug ID |
D02YCH
|
| NDC Product Code |
66127-100 |
| UNII |
2NX48Z0A9G
|
| Synonyms |
Icodextrin | Extraneal | Icodial |
|
| Chemical Information |
| Molecular Formula |
C8H8Cl2N4 |
| CAS Registry Number |
5051-62-7 |
| SMILES |
C1=CC(=C(C(=C1)Cl)C=NN=C(N)N)Cl |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
|
|
|
