Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Icosapent
Drug ID BADD_D01125
Description Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Indications and Usage EPA can be used for lowering elevated triglycerides in those who are hyperglyceridemic. In addition, EPA may play a therapeutic role in patients with cystic fibrosis by reducing disease severity and may play a similar role in type 2 diabetics in slowing the progression of diabetic nephropathy.
Marketing Status approved; nutraceutical
ATC Code Not Available
DrugBank ID DB00159
KEGG ID D08061
MeSH ID D015118
PubChem ID 446284
TTD Drug ID Not Available
NDC Product Code Not Available
UNII AAN7QOV9EA
Synonyms Eicosapentaenoic Acid | 5,8,11,14,17-Eicosapentaenoic Acid | Eicosapentanoic Acid | Acid, Eicosapentanoic | omega-3-Eicosapentaenoic Acid | omega 3 Eicosapentaenoic Acid | Timnodonic Acid | Icosapent | 5,8,11,14,17-Icosapentaenoic Acid
Chemical Information
Molecular Formula C20H30O2
CAS Registry Number 10417-94-4
SMILES CCC=CCC=CCC=CCC=CCC=CCCCC(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Arthralgia15.01.02.001--
Musculoskeletal discomfort15.03.04.001--Not Available
Oropharyngeal pain22.12.03.016; 07.05.05.004--
The 1th Page    1    Total 1 Pages
ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene