Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Iloprost
Drug ID BADD_D01135
Description Iloprost is a synthetic analogue of prostacyclin PGI2 that dilates systemic and pulmonary arterial vascular beds. It is used to treat pulmonary arterial hypertension (PAH).
Indications and Usage Used for the treatment of pulmonary arterial hypertension.
Marketing Status approved; investigational
ATC Code B01AC11
DrugBank ID DB01088
KEGG ID D02721
MeSH ID D016285
PubChem ID 5311181
TTD Drug ID D05ZTH
NDC Product Code 66215-303; 40016-013; 82231-109; 54893-0017; 66215-302
UNII JED5K35YGL
Synonyms Iloprost | Ciloprost | ZK-36374 | ZK 36374 | ZK36374 | Ventavis
Chemical Information
Molecular Formula C22H32O4
CAS Registry Number 78919-13-8
SMILES CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.0010.000551%
Acute respiratory failure22.02.06.001; 14.01.04.0040.000164%Not Available
Amnesia19.20.01.001; 17.03.02.0010.000206%
Angina pectoris24.04.04.002; 02.02.02.0020.000164%
Angina unstable24.04.04.004; 02.02.02.0040.000082%Not Available
Arrhythmia02.03.02.0010.000493%Not Available
Ascites09.01.05.003; 07.07.01.001; 02.05.04.0020.000493%
Asphyxia12.01.08.011; 22.02.02.0010.000329%Not Available
Asthenia08.01.01.0010.001760%Not Available
Atrial flutter02.03.03.0030.000082%
Back pain15.03.04.005--
Blindness unilateral06.02.10.007; 17.17.01.0160.000082%Not Available
Blood pressure fluctuation24.06.01.0020.000123%Not Available
Breast pain21.05.05.0030.000082%
Bronchospasm22.03.01.004; 10.01.03.012--
Cardiac arrest02.03.04.0010.001809%
Cardiac failure02.05.01.0010.001974%
Cardiac failure congestive02.05.01.0020.000576%Not Available
Cardio-respiratory arrest22.02.06.007; 02.03.04.0020.001110%Not Available
Cardiomegaly02.04.02.0010.000164%Not Available
Cardiovascular disorder02.11.01.010; 24.03.02.0090.000345%Not Available
Cerebral haemorrhage17.08.01.003; 24.07.04.0010.000329%Not Available
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.0090.000633%Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.0110.001398%Not Available
Choking22.12.03.0030.000329%Not Available
Cholelithiasis09.03.01.0020.000247%Not Available
Chronic obstructive pulmonary disease22.03.01.0070.000452%Not Available
Circulatory collapse24.06.02.0010.000452%Not Available
Colon cancer16.13.01.001; 07.21.01.0010.000082%Not Available
Coma17.02.09.0010.000247%Not Available
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