ADReCS

Pharmaceutical Information

Drug Name	Indinavir
Drug ID	BADD_D01150
Description	A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Indications and Usage	Indinavir is an antiretroviral drug for the treatment of HIV infection.
Marketing Status	approved
ATC Code	J05AE02
DrugBank ID	DB00224
KEGG ID	D03833
MeSH ID	D019469
PubChem ID	5362440
TTD Drug ID	D0V7CF
NDC Product Code	Not Available
UNII	5W6YA9PKKH
Synonyms	Indinavir \| MK-639 \| MK 639 \| MK639 \| L-735 524 \| L 735 524 \| L735 524 \| L-735,524 \| L 735,524 \| L735,524 \| Crixivan \| Indinavir Sulfate \| Sulfate, Indinavir \| Indinavir, Sulfate (1:1)

Chemical Information

Molecular Formula	C36H47N5O4
CAS Registry Number	150378-17-9
SMILES	CC(C)(C)NC(=O)C1CN(CCN1CC(CC(CC2=CC=CC=C2)C(=O)NC3C(CC4=CC=CC=C34)O)O)CC5=CN=CC= C5
Chemical Structure

ADRs Induced by Drug

*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Abdominal distension	07.01.04.001	-	-
Abdominal pain	07.01.05.002	-	-
Accommodation disorder	06.02.04.001	-	-	Not Available
Acquired immunodeficiency syndrome	11.05.17.007; 10.03.03.001	-	-	Not Available
Agitation	17.02.05.012; 19.06.02.001	-	-
Alanine aminotransferase increased	13.03.04.005	-	-
Alopecia	23.02.02.001	-	-
Amylase increased	13.05.01.009	-	-
Anaemia	01.03.02.001	-	-
Anaphylactic shock	24.06.02.004; 10.01.07.002	-	-	Not Available
Anaphylactoid reaction	10.01.07.003; 24.06.03.007	-	-	Not Available
Angina pectoris	24.04.04.002; 02.02.02.002	-	-
Angioedema	22.04.02.008; 23.04.01.001; 10.01.05.009	-	-	Not Available
Anxiety	19.06.02.002	-	-
Aphthous ulcer	07.05.06.002	-	-	Not Available
Arthralgia	15.01.02.001	-	-
Aspartate aminotransferase increased	13.03.04.011	-	-
Asthenia	08.01.01.001	-	-	Not Available
Back pain	15.03.04.005	-	-
Bacteraemia	11.01.11.001	-	-
Blood bilirubin unconjugated increased	13.03.04.020	-	-	Not Available
Blood cholesterol increased	13.12.01.002	-	-
Blood creatinine increased	13.13.01.004	-	-
Blood glucose increased	13.02.02.002	-	-	Not Available
Blood triglycerides increased	13.12.03.001	-	-	Not Available
Body temperature increased	13.15.01.001	-	-	Not Available
Breath odour	07.01.06.002	-	-	Not Available
Bruxism	19.11.03.001; 07.01.06.008	-	-	Not Available
Calculus urinary	20.04.03.002	-	-	Not Available
Cardiovascular disorder	02.11.01.010; 24.03.02.009	-	-	Not Available

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