Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Interferon beta-1b
Drug ID BADD_D01170
Description Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Indications and Usage Interferon beta-1b is a drug used for the treatment of relapsing/remitting multiple sclerosis. It has been shown to slow the advance of the disease as well as to decrease the frequency of attacks.
Marketing Status approved
ATC Code L03AB08
DrugBank ID DB00068
KEGG ID D00746
MeSH ID D000068576
PubChem ID Not Available
TTD Drug ID D0CQ2O
NDC Product Code 0078-0569; 50419-524
UNII TTD90R31WZ
Synonyms Interferon beta-1b | Beta-IFN-1b | Ser(17) IFN-beta | Interferon Beta, Serine(17) | Serine(17) Interferon Beta | Interferon beta 1b | IFN-Beta Ser | Interferon Beta, Ser(17) | Betaseron | Beta-Seron | Beta Seron | Extavia | Betaferon
Chemical Information
Molecular Formula Not Available
CAS Registry Number 145155-23-3
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Alanine aminotransferase increased13.03.04.005--
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Blood triglycerides increased13.12.03.001--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Capillary leak syndrome08.01.07.012; 24.06.03.001--
Cardiomyopathy02.04.01.001--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Confusional state17.02.03.005; 19.13.01.001--
Coordination abnormal17.02.02.004--Not Available
Death08.04.01.001--
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.007--
Dyspnoea02.11.05.003; 22.02.01.004--
Gamma-glutamyltransferase increased13.03.04.024--
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hepatitis09.01.07.004--Not Available
Hypertension24.08.02.001--
Hyperthyroidism14.11.01.011; 05.02.02.001--
Hypertonia15.05.04.007; 17.05.02.001--Not Available
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