Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iodixanol
Drug ID BADD_D01178
Description Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Indications and Usage Iodixanol is a contrast agent during coronary angiography.
Marketing Status approved
ATC Code V08AB09
DrugBank ID DB01249
KEGG ID D01474
MeSH ID C044834
PubChem ID 3724
TTD Drug ID D0Y4YG
NDC Product Code 71806-222; 65219-381; 0407-2223; 65219-383; 0407-2222; 57884-0029
UNII HW8W27HTXX
Synonyms iodixanol | Visipaque | Visipaque Unique Softpac | iodixanol-320 | contrast media 2-5410-3
Chemical Information
Molecular Formula C35H44I6N6O15
CAS Registry Number 92339-11-2
SMILES CC(=O)N(CC(CN(C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I)C(=O)C)O)C2=C(C(= C(C(=C2I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Epilepsy17.12.03.002--Not Available
Erythema23.03.06.0010.525679%Not Available
Erythema multiforme23.03.01.003; 10.01.03.0150.040546%
Extrasystoles02.03.02.003--Not Available
Extravasation08.01.03.0080.066866%Not Available
Eye disorder06.08.03.001--Not Available
Eye irritation06.04.05.0030.019206%Not Available
Eye swelling06.08.03.0030.073979%Not Available
Eyelid oedema23.04.01.003; 10.01.05.001; 06.04.04.0040.092474%Not Available
Face oedema08.01.07.003; 23.04.01.004; 10.01.05.0020.085361%
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Feeling cold08.01.09.0080.007113%Not Available
Feeling hot08.01.09.0090.091051%Not Available
Flushing23.06.05.003; 08.01.03.025; 24.03.01.0020.193484%
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Generalised oedema14.05.06.007; 08.01.07.0040.007113%
Haematoma24.07.01.001--
Haematuria24.07.01.047; 20.02.01.006; 21.10.01.018--
Head discomfort17.02.05.0270.019206%Not Available
Headache17.14.01.001--
Hemiparesis17.01.04.0010.014227%
Hemiplegia17.01.04.0020.010670%Not Available
Henoch-Schonlein purpura10.02.02.004; 23.06.01.002; 01.01.04.001; 24.07.06.0030.035567%Not Available
Hyperaemia24.03.02.0020.007113%Not Available
Hyperhidrosis23.02.03.004; 08.01.03.0280.074691%
Hypersensitivity10.01.03.0030.182103%
Hypertension24.08.02.001--
Hyperthermia12.05.01.002; 08.05.01.0010.010670%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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