Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Isoflurane
Drug ID BADD_D01203
Description A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Indications and Usage For induction and maintenance of general anesthesia.
Marketing Status approved; vet_approved
ATC Code N01AB06
DrugBank ID DB00753
KEGG ID D00545
MeSH ID D007530
PubChem ID 3763
TTD Drug ID D0DP6L
NDC Product Code 42677-114; 12164-012; 66794-019; 12164-002; 66794-011; 10019-360; 66794-017; 66794-020; 65085-0019
UNII CYS9AKD70P
Synonyms Isoflurane
Chemical Information
Molecular Formula C3H2ClF5O
CAS Registry Number 26675-46-7
SMILES C(C(F)(F)F)(OC(F)F)Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation19.06.02.001; 17.02.05.012--
Aphasia19.21.01.001; 17.02.03.0010.000179%
Arrhythmia02.03.02.001--Not Available
Body temperature increased13.15.01.001--Not Available
Breath holding22.02.01.016; 19.01.01.002--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Carbon dioxide increased13.02.01.011--Not Available
Cardiac arrest02.03.04.0010.000268%
Chills15.05.03.016; 08.01.09.001--
Chromaturia20.02.01.0020.000179%
Cough22.02.03.001--
Delirium19.13.02.001--
Dermatitis23.03.04.002--Not Available
Drug abuse19.07.06.0100.000179%Not Available
Hallucination19.10.04.003--
Hepatic failure09.01.03.002--
Hepatic function abnormal09.01.02.001--Not Available
Hepatic necrosis09.01.07.002--
Hepatitis09.01.07.004--Not Available
Hepatocellular injury09.01.07.008--Not Available
Hiccups22.12.01.001; 07.01.06.009--
Hypercapnia22.02.02.002; 14.01.04.0010.000179%Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperkalaemia14.05.03.001--
Hypertension24.08.02.0010.000572%
Hyperthermia malignant08.05.01.0020.000179%Not Available
Hyperventilation19.01.02.004; 22.02.01.0060.000179%Not Available
Hypotension24.06.03.0020.000179%
Ileus07.13.01.001--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
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