Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Isoflurane
Drug ID BADD_D01203
Description A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Indications and Usage For induction and maintenance of general anesthesia.
Marketing Status approved; vet_approved
ATC Code N01AB06
DrugBank ID DB00753
KEGG ID D00545
MeSH ID D007530
PubChem ID 3763
TTD Drug ID D0DP6L
NDC Product Code 42677-114; 12164-012; 66794-019; 12164-002; 66794-011; 10019-360; 66794-017; 66794-020; 65085-0019
UNII CYS9AKD70P
Synonyms Isoflurane
Chemical Information
Molecular Formula C3H2ClF5O
CAS Registry Number 26675-46-7
SMILES C(C(F)(F)F)(OC(F)F)Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Laryngospasm22.04.02.002--
Muscle rigidity17.05.02.005; 15.05.04.001--Not Available
Mutism19.19.01.001; 17.02.08.0070.000179%Not Available
Nausea07.01.07.001--
Necrosis24.04.02.006; 08.03.03.001--Not Available
Oligohydramnios18.05.01.0010.000179%Not Available
Rash23.03.13.001--Not Available
Respiratory acidosis14.01.04.002; 22.02.02.0040.000572%Not Available
Respiratory arrest22.02.01.0090.000179%Not Available
Respiratory depression17.02.05.047; 22.02.01.010--Not Available
Rhythm idioventricular02.03.04.019--Not Available
Salivary hypersecretion07.06.01.009--Not Available
Supraventricular tachycardia02.03.03.0120.000268%
Tachycardia02.03.02.0070.000572%Not Available
Tearfulness19.15.02.0050.000179%Not Available
Ventricular arrhythmia02.03.04.006--
Vomiting07.01.07.003--
White blood cell count increased13.01.06.013--Not Available
Postoperative ileus12.02.03.012; 07.02.05.004--Not Available
Cerebral disorder17.02.10.0170.000447%Not Available
Cardiac disorder02.11.01.003--Not Available
Pulmonary function test decreased13.19.01.001--Not Available
Hepatobiliary disease09.01.08.003--Not Available
Liver injury09.01.07.022; 12.01.17.012--Not Available
Traumatic liver injury09.01.08.010; 12.01.17.027--Not Available
Slow response to stimuli17.02.05.0630.000179%Not Available
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