Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Levalbuterol hydrochloride
Drug ID BADD_D01263
Description Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). [Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects have led to the development of an enantiomerically pure (R)-salbutamol formulation known as levosalbutamol (levalbuterol).
Indications and Usage Indicated for the management of COPD (chronic obstructive pulmonary disease, also known as chronic obstructive lung disease) and asthma.
Marketing Status approved; investigational
ATC Code Not Available
DrugBank ID DB13139
KEGG ID D02281
MeSH ID D064412
PubChem ID 123601
TTD Drug ID D02ZJI
NDC Product Code 51927-5157; 17478-171; 17478-172; 35573-444; 35573-443; 17478-173; 76204-700; 15308-0310; 48954-719; 53104-7719; 17478-174; 17337-0524; 0115-9930; 35573-445; 0115-9932; 50090-6377; 76204-800; 76204-900; 0115-9931
UNII WDQ1526QJM
Synonyms Levalbuterol | Xopenex | Levalbuterol Hydrochloride | Hydrochloride, Levalbuterol | Levosalbutamol Hydrochloride | Hydrochloride, Levosalbutamol
Chemical Information
Molecular Formula C13H22ClNO3
CAS Registry Number 50293-90-8
SMILES CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lymphadenopathy01.09.01.002--Not Available
Metabolic acidosis14.01.01.003--Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Muscle spasms15.05.03.004--
Myalgia15.05.02.001--
Nasal oedema22.04.03.012--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Otitis media11.01.05.004; 04.05.01.001--
Pain08.01.08.004--
Paraesthesia23.03.03.094; 17.02.06.005--
Pharyngitis11.01.13.003; 07.05.07.004; 22.07.03.004--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Sinusitis22.07.03.007; 11.01.13.005--
Supraventricular tachycardia02.03.03.012--
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tachycardia02.03.02.007--Not Available
Tremor17.01.06.002--
Urticaria23.04.02.001; 10.01.06.001--
Viral infection11.05.04.001--Not Available
Eye pruritus06.04.05.006--Not Available
Electrocardiogram change13.14.05.014--Not Available
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