Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Levocarnitine
Drug ID BADD_D01271
Description Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Indications and Usage For treatment of primary systemic carnitine deficiency, a genetic impairment of normal biosynthesis or utilization of levocarnitine from dietary sources, or for the treatment of secondary carnitine deficiency resulting from an inborn error of metabolism such as glutaric aciduria II, methyl malonic aciduria, propionic acidemia, and medium chain fatty acylCoA dehydrogenase deficiency. Used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias. Parenteral levocarnitine is indicated for the prevention and treatment of carnitine deficiency in patients with end-stage renal disease.
Marketing Status approved; investigational
ATC Code A16AA01
DrugBank ID DB00583
KEGG ID D02176
MeSH ID D002331
PubChem ID 10917
TTD Drug ID D0G8SQ
NDC Product Code 81999-0005; 50383-171; 50383-172; 54482-147; 54482-148; 54482-145; 54482-144; 0143-9852; 52817-830; 58116-010; 59380-018; 64980-503; 0517-1045; 51927-0240; 70954-492; 49452-1778; 51927-1865; 16571-762; 58159-089; 42765-049; 76055-1005
UNII 0G389FZZ9M
Synonyms Carnitine | Levocarnitine | Vitamin BT | L-Carnitine | L Carnitine | Bicarnesine
Chemical Information
Molecular Formula C7H15NO3
CAS Registry Number 541-15-1
SMILES C[N+](C)(C)CC(CC(=O)[O-])O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Gastrointestinal pain07.01.05.005--
Haemoglobin13.01.05.018--Not Available
Headache17.14.01.001--
Hepatic encephalopathy09.01.03.006; 17.13.01.0030.004312%Not Available
Hypercalcaemia14.04.01.003; 05.04.01.002--
Hyperkalaemia14.05.03.001--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.0010.004312%
Hyperthermia12.05.01.002; 08.05.01.0010.004312%Not Available
Hyperthyroidism14.11.01.011; 05.02.02.0010.012937%
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hypervolaemia02.05.04.019; 14.05.06.003--Not Available
Hypoglycaemia14.06.03.001; 05.06.03.0010.004312%
Hypotension24.06.03.002--
Impaired gastric emptying07.02.02.004--
Infection11.01.08.002--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Injection site reaction12.07.03.015; 08.02.03.014--
Injury12.01.08.004--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Melaena24.07.02.013; 07.12.02.004--Not Available
Muscle spasms15.05.03.004--
Muscular weakness17.05.03.005; 15.05.06.001--
Myalgia15.05.02.001--
Nausea07.01.07.0010.004312%
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Pain08.01.08.004--
Palpitations02.11.04.012--
Paraesthesia23.03.03.094; 17.02.06.005--
Parathyroid disorder05.04.03.001--Not Available
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