Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Levomefolate calcium
Drug ID BADD_D01277
Description Not Available
Indications and Usage Not Available
Marketing Status Not Available
ATC Code Not Available
DrugBank ID Not Available
KEGG ID D09354
MeSH ID C569381
PubChem ID 135564391
TTD Drug ID Not Available
NDC Product Code 58159-062; 43615-002; 69723-002; 54239-008; 51927-5180; 80680-001
UNII A9R10K3F2F
Synonyms levomefolate calcium | N-(4-(((2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid calcium salt | safyral | metafolin
Chemical Information
Molecular Formula C20H23CaN7O6
CAS Registry Number 151533-22-1
SMILES CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Breast pain21.05.05.003--
Breast tenderness21.05.05.004--Not Available
Cardiovascular disorder02.11.01.010; 24.03.02.009--Not Available
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chloasma23.05.01.001; 18.08.02.002--Not Available
Depressed mood19.15.02.001--Not Available
Depression19.15.01.001--
Embolism arterial24.01.01.014--
Embolism venous24.01.01.003--Not Available
Gallbladder disorder09.03.02.001--Not Available
Headache17.14.01.001--
Hyperkalaemia14.05.03.001--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Irritability19.04.02.013; 08.01.03.011--
Liver disorder09.01.08.001--Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Mood altered19.04.02.007--Not Available
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Premenstrual syndrome19.04.02.009; 17.14.01.019; 21.01.01.007--Not Available
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Retinal vein occlusion24.01.07.006; 06.10.01.010--Not Available
Superior sagittal sinus thrombosis24.01.04.004; 17.08.03.001--Not Available
Tenderness08.01.08.005--Not Available
Uterine haemorrhage24.07.03.004; 21.07.01.005--
Uterine leiomyoma21.07.02.004; 16.04.02.001--Not Available
Vomiting07.01.07.003--
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