| Pharmaceutical Information |
| Drug Name |
Lithium cation |
| Drug ID |
BADD_D01304 |
| Description |
Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also be used to augment other antidepressant drugs. It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several critical neuronal enzymes and neurotransmitter receptors. |
| Indications and Usage |
Lithium, in its salt forms, is used as a mood stabilizer and for the treatment of depression and mania. It is most frequently prescribed in the treatment of bipolar disorder. |
| Marketing Status |
experimental |
| ATC Code |
N05AN01 |
| DrugBank ID |
DB01356
|
| KEGG ID |
D08133
|
| MeSH ID |
D008094
|
| PubChem ID |
28486
|
| TTD Drug ID |
D5MF8Y
|
| NDC Product Code |
Not Available |
| UNII |
8H8Z5UER66
|
| Synonyms |
Lithium | Lithium-7 | Lithium 7 |
|
| Chemical Information |
| Molecular Formula |
Li+ |
| CAS Registry Number |
17341-24-1 |
| SMILES |
[Li+] |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
|
|
|
