Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lomefloxacin hydrochloride
Drug ID BADD_D01310
Description Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.
Indications and Usage For the treatment of bacterial infections of the respiratory tract (chronic bronchitis) and urinary tract, and as a pre-operative prophylactic to prevent urinary tract infection caused by: S.pneumoniae, H.influenzae, S.aureus, P.aeruginosa, E. cloacae, P. mirabilis, C. civersus, S. asprphyticus, E.coli, and K.pneumoniae.
Marketing Status approved; investigational
ATC Code S01AE04; J01MA07
DrugBank ID DB00978
KEGG ID D00873
MeSH ID C053091
PubChem ID 68624
TTD Drug ID D02KOF
NDC Product Code Not Available
UNII 9VC7S3ZXXB
Synonyms lomefloxacin | lomenfloxacin | 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid | lomefloxacin hydrochloride | Maxaquin | Logiflox | Ocacin | Okacin | Okacyn | SC 4711 | SC-4711 | Décalogiflox | NY 198 | NY-198
Chemical Information
Molecular Formula C17H20ClF2N3O3
CAS Registry Number 98079-52-8
SMILES CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Acne23.02.01.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.001--Not Available
Alanine aminotransferase increased13.03.04.005--
Albuminuria20.02.01.001--Not Available
Anaemia01.03.02.001--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009--Not Available
Anuria20.01.03.002--Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001--
Aspartate aminotransferase13.03.04.008--Not Available
Asthenia08.01.01.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Back pain15.03.04.005--
Blood albumin increased13.09.01.002--Not Available
Blood alkaline phosphatase13.04.02.010--Not Available
Blood bilirubin13.03.04.015--Not Available
Blood cholesterol increased13.12.01.002--
Blood creatinine increased13.13.01.004--
Blood glucose increased13.02.02.002--Not Available
Blood potassium decreased13.11.01.010--Not Available
Blood potassium increased13.11.01.011--Not Available
Blood triglycerides increased13.12.03.001--Not Available
Blood urea increased13.13.01.006--Not Available
Bradycardia02.03.02.002--Not Available
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