Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lurasidone
Drug ID BADD_D01330
Description Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Indications and Usage Treatment of schizophrenia.
Marketing Status approved; investigational
ATC Code N05AE05
DrugBank ID DB08815
KEGG ID D04820
MeSH ID D000069056
PubChem ID 213046
TTD Drug ID D01QGX
NDC Product Code 50370-0036
UNII 22IC88528T
Synonyms Lurasidone Hydrochloride | Hydrochloride, Lurasidone | Lurasidone HCl | HCl, Lurasidone | SM 13496 | 13496, SM | SM13496 | SM-13,496 | SM 13,496 | SM13,496 | SM-13496 | Lurasidone | N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide | Latuda
Chemical Information
Molecular Formula C28H36N4O2S
CAS Registry Number 367514-87-2
SMILES C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Suicidal behaviour19.12.01.006--Not Available
Activation syndrome19.06.02.008; 17.02.05.0410.004230%Not Available
Psychiatric decompensation19.01.02.0100.000984%Not Available
Dementia with Lewy bodies17.03.01.004; 19.20.02.003--Not Available
Oromandibular dystonia17.01.03.0060.000721%Not Available
Oropharyngeal pain22.12.03.016; 07.05.05.004--
Umbilical cord around neck18.04.14.0040.000492%Not Available
Violence-related symptom19.05.01.0220.000492%Not Available
Tachyphrenia19.10.03.010; 17.03.03.0070.001672%Not Available
Excessive eye blinking17.17.02.010; 06.05.01.0040.000492%Not Available
Attention deficit hyperactivity disorder19.21.04.0040.001672%Not Available
Drug effect less than expected08.06.01.0360.001115%Not Available
Drug effective for unapproved indication12.09.02.001; 08.06.01.0370.000492%Not Available
Drug ineffective for unapproved indication12.09.02.002; 08.06.01.0380.003443%Not Available
Hypoprolactinaemia05.03.02.0080.001115%Not Available
Manic symptom19.16.02.0030.000721%Not Available
Psychotic symptom19.03.01.0120.000492%Not Available
Therapeutic product effect incomplete08.06.01.0520.002394%Not Available
Therapeutic product effect increased08.06.01.0530.003345%Not Available
Therapy partial responder08.06.01.0640.001115%Not Available
Treatment noncompliance12.09.02.006; 08.06.01.0670.001869%Not Available
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