Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lurasidone
Drug ID BADD_D01330
Description Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Indications and Usage Treatment of schizophrenia.
Marketing Status approved; investigational
ATC Code N05AE05
DrugBank ID DB08815
KEGG ID D04820
MeSH ID D000069056
PubChem ID 213046
TTD Drug ID D01QGX
NDC Product Code 50370-0036
UNII 22IC88528T
Synonyms Lurasidone Hydrochloride | Hydrochloride, Lurasidone | Lurasidone HCl | HCl, Lurasidone | SM 13496 | 13496, SM | SM13496 | SM-13,496 | SM 13,496 | SM13,496 | SM-13496 | Lurasidone | N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide | Latuda
Chemical Information
Molecular Formula C28H36N4O2S
CAS Registry Number 367514-87-2
SMILES C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypomania19.16.02.0010.006296%Not Available
Hyponatraemia14.05.04.0020.001213%
Hypotension24.06.03.002--
Ileus paralytic07.02.05.0010.000328%Not Available
Increased appetite14.03.01.003; 08.01.09.0270.001672%Not Available
Infection11.01.08.002--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Insomnia19.02.01.002; 17.15.03.0020.006952%
Intentional self-injury19.12.01.002; 12.01.08.0360.000820%Not Available
Irritability19.04.02.013; 08.01.03.0110.005345%
Jaundice neonatal18.04.08.001; 09.01.01.008; 01.06.04.0060.000328%Not Available
Joint stiffness15.01.02.003--Not Available
Ketoacidosis14.01.01.0080.000328%Not Available
Laryngospasm22.04.02.0020.000328%
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
Leukopenia01.02.02.0010.000656%Not Available
Libido decreased21.03.02.005; 19.08.03.0010.001672%
Lip swelling07.05.04.005; 23.04.01.007; 10.01.05.0050.001935%Not Available
Lip ulceration07.05.06.0120.000721%Not Available
Loss of consciousness17.02.04.0040.001312%Not Available
Malaise08.01.01.0030.010297%
Mania19.16.02.0020.015150%
Menopausal symptoms21.02.02.002--Not Available
Mental impairment19.21.02.003; 17.03.03.0020.000328%Not Available
Middle insomnia19.02.01.003; 17.15.03.0030.001672%Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Mood altered19.04.02.0070.001279%Not Available
Mood swings19.04.03.0010.001672%Not Available
Movement disorder17.01.02.0100.001836%Not Available
Muscle rigidity17.05.02.005; 15.05.04.0010.002164%Not Available
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