Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mafenide
Drug ID BADD_D01337
Description Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns.
Indications and Usage Indicated for use as an adjunctive topical antimicrobial agent to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.[label]
Marketing Status approved; vet_approved
ATC Code D06BA03
DrugBank ID DB06795
KEGG ID D02351
MeSH ID D008272
PubChem ID 3998
TTD Drug ID D0K1QD
NDC Product Code Not Available
UNII 58447S8P4L
Synonyms Mafenide | Maphenid | Mafenide Acetate | Sulfamylon | Marfanil | Napaltan | 4-Homosulfanilamide | 4 Homosulfanilamide | Sulfabenzamine | Bensulfamide | Mafylon
Chemical Information
Molecular Formula C7H10N2O2S
CAS Registry Number 138-39-6
SMILES C1=CC(=CC=C1CN)S(=O)(=O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acidosis14.01.03.002--
Blister23.03.01.001; 12.01.06.002--Not Available
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
Diarrhoea07.02.01.001--
Disseminated intravascular coagulation24.01.01.010; 01.01.02.002--
Eosinophilia01.02.04.001--
Erythema23.03.06.001--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Glucose-6-phosphate dehydrogenase deficiency14.14.03.001; 03.08.03.001; 01.06.05.001--Not Available
Haemoglobin13.01.05.018--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Hyperventilation22.02.01.006; 19.01.02.004--Not Available
Metabolic acidosis14.01.01.003--Not Available
Pain08.01.08.004--
Pancytopenia01.03.03.003--Not Available
PCO213.02.01.017--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Swelling08.01.03.015--Not Available
Tachypnoea22.02.01.014--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Skin maceration23.03.03.016--Not Available
Haemorrhage24.07.01.002--Not Available
Porphyrin metabolism disorder14.14.01.006; 03.08.01.006; 09.01.10.004--Not Available
Skin abrasion12.01.06.010; 23.03.11.018--Not Available
Bone marrow failure01.03.03.005--
Accidental exposure to product12.09.01.001--Not Available
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ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene