Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Magnesium hydroxide
Drug ID BADD_D01342
Description Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially as a fire retardant. It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers).
Indications and Usage Magnesium hydroxide can be used as an antacid or a laxative depending on the administered dose. As an antacid, it is used for the temporary relief of heartburn, upset stomach, sour stomach or acid indigestion. As a laxative, it is used for the relief of occasional constipation by promoting bowel movements for 30 minutes and up to 6 hours.
Marketing Status approved; investigational
ATC Code A02AA04; G04BX01
DrugBank ID DB09104
KEGG ID D00731
MeSH ID D008276
PubChem ID 14791
TTD Drug ID Not Available
NDC Product Code 79481-0648; 12784-191; 12784-201; 12784-441; 11822-3329; 41167-0256; 46122-437; 49035-636; 55154-4061; 55319-738; 57237-314; 70677-1073; 0904-6757; 12784-181; 12784-196; 0113-7332; 37808-064; 37808-332; 49035-307; 50804-647; 62011-0124; 0363-1634; 69842-332; 70000-0064; 70677-0043; 70677-1072; 12784-192; 12784-435; 12784-448; 14335-300; 67417-222; 36800-684; 0121-0940; 41250-332; 41520-396; 50804-648; 50804-649; 60687-429; 0363-0649; 0363-1099; 0363-9129; 63941-647; 68016-850; 68788-8413; 70518-3481; 70677-0044; 12784-179; 12784-434; 12784-459; 67417-243; 0121-0431; 37808-901; 41250-949; 46122-435; 46122-436; 70000-0061; 72476-661; 80447-649; 12784-458; 41167-0265; 50594-015; 55910-396; 62011-0123; 0363-1648; 70518-3351; 70677-1074; 12784-188; 11822-0399; 30142-547; 37808-889; 41167-0291; 41167-0292; 49348-171; 49348-305; 63868-310; 63941-648; 69842-278; 70518-3406; 79481-0647; 12784-449; 12784-456; 67417-223; 67417-236; 36800-674; 41520-949; 49035-649; 55154-4160; 0363-0647; 63868-787; 0395-1672; 66689-053; 69842-912; 0904-0788; 12784-180; 41167-0259; 55910-649; 56062-727; 57896-647; 63868-788; 70000-0027; 70000-0065; 0536-1319; 0536-2470; 0904-6756; 12784-178; 50917-840; 55603-661; 21130-649; 30142-649; 41163-949; 41167-0260; 56062-649; 63941-649; 69339-153; 69842-318; 72476-665; 12784-177; 12784-197; 12784-198; 36800-649; 0132-0655; 41167-0257; 55319-548; 57896-648; 57896-649
UNII NBZ3QY004S
Synonyms Magnesium Hydroxide | Hydroxide, Magnesium | Magnesium Hydrate | Hydrate, Magnesium | Magnesium Hydroxide (Mg(OH)4) | Brucite
Chemical Information
Molecular Formula H2MgO2
CAS Registry Number 1317-43-7
SMILES [OH-].[OH-].[Mg+2]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.022016%
Apnoea22.02.01.0010.008806%
Asthenia08.01.01.0010.013210%Not Available
Atrial fibrillation02.03.03.0020.013210%
Bradycardia02.03.02.0020.013210%Not Available
Cardiac arrest02.03.04.0010.008806%
Cholelithiasis09.03.01.0020.008806%Not Available
Constipation07.02.02.0010.017613%
Deafness04.02.01.0010.008806%Not Available
Dehydration14.05.05.0010.022016%
Depression19.15.01.0010.008806%
Diarrhoea07.02.01.0010.022016%
Drug abuse19.07.06.0100.008806%Not Available
Drug ineffective08.06.01.0060.038748%Not Available
Drug interaction08.06.03.0010.026419%Not Available
Eye discharge06.04.05.0010.008806%Not Available
Fatigue08.01.01.0020.008806%
Gait disturbance17.02.05.016; 08.01.02.002; 15.03.05.0130.008806%
Gastric ulcer haemorrhage24.07.02.003; 07.04.03.005--Not Available
Gastritis07.08.02.0010.008806%
Gastrointestinal disorder07.11.01.0010.008806%Not Available
Haematemesis24.07.02.011; 07.12.02.002--Not Available
Haemorrhoids24.10.02.002; 07.15.03.0010.008806%
Headache17.14.01.0010.008806%
Hyperglycaemia05.06.02.002; 14.06.02.0020.008806%
Hypermagnesaemia14.04.02.0020.039629%
Hypokalaemia14.05.03.0020.008806%
Hyponatraemia14.05.04.0020.013210%
Hypotension24.06.03.0020.022016%
Hypothermia08.05.01.003; 12.05.03.0010.008806%
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