Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mebendazole
Drug ID BADD_D01353
Description A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Indications and Usage For the treatment of Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections.
Marketing Status approved; vet_approved
ATC Code P02CA01
DrugBank ID DB00643
KEGG ID D00368
MeSH ID D008463
PubChem ID 4030
TTD Drug ID D0J1MI
NDC Product Code 59285-011; 90027-001; 73309-120; 71052-168; 12578-618; 64896-669; 72643-035; 82891-003; 69766-038; 50458-675; 53104-7510
UNII 81G6I5V05I
Synonyms Mebendazole | Vermidil | Wormkuur | Anti-Worm | Anti Worm | Bantenol | Banworm | Boots Threadworm Treatment | Lomper | Madicure | Mebendan | Mebenvet | Pripsen Mebendazole | R17635 | Sqworm | Sufil | Telmin | Vermicol | Surfont | Vermox
Chemical Information
Molecular Formula C16H13N3O3
CAS Registry Number 31431-39-7
SMILES COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.036733%
Abdominal pain upper07.01.05.0030.007871%
Abortion spontaneous18.01.04.0010.005248%Not Available
Agranulocytosis01.02.03.001--Not Available
Alanine aminotransferase increased13.03.04.005--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.0010.005248%Not Available
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.0010.005248%Not Available
Ataxia17.02.02.001; 08.01.02.0040.005248%
Confusional state19.13.01.001; 17.02.03.0050.005248%
Dehydration14.05.05.0010.005248%
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.0010.018367%
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.0030.034109%
Dyspnoea02.11.05.003; 22.02.01.0040.005248%
Fatigue08.01.01.0020.010495%
Gamma-glutamyltransferase increased13.03.04.024--
Gastrointestinal disorder07.11.01.0010.005248%Not Available
Gastrointestinal pain07.01.05.005--
Hallucination19.10.04.0030.005248%
Headache17.14.01.0010.013119%
Hepatitis09.01.07.004--Not Available
Hepatocellular injury09.01.07.0080.005248%Not Available
Hyperhidrosis23.02.03.004; 08.01.03.0280.005248%
Hypersensitivity10.01.03.003--
Intentional self-injury19.12.01.002; 12.01.08.0360.007871%Not Available
Malaise08.01.01.0030.005248%
Muscular weakness17.05.03.005; 15.05.06.0010.020990%
Nausea07.01.07.0010.037783%
Neutropenia01.02.03.004--Not Available
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