Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mebendazole
Drug ID BADD_D01353
Description A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Indications and Usage For the treatment of Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections.
Marketing Status approved; vet_approved
ATC Code P02CA01
DrugBank ID DB00643
KEGG ID D00368
MeSH ID D008463
PubChem ID 4030
TTD Drug ID D0J1MI
NDC Product Code 59285-011; 90027-001; 73309-120; 71052-168; 12578-618; 64896-669; 72643-035; 82891-003; 69766-038; 50458-675; 53104-7510
UNII 81G6I5V05I
Synonyms Mebendazole | Vermidil | Wormkuur | Anti-Worm | Anti Worm | Bantenol | Banworm | Boots Threadworm Treatment | Lomper | Madicure | Mebendan | Mebenvet | Pripsen Mebendazole | R17635 | Sqworm | Sufil | Telmin | Vermicol | Surfont | Vermox
Chemical Information
Molecular Formula C16H13N3O3
CAS Registry Number 31431-39-7
SMILES COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pain in extremity15.03.04.0100.020990%
Pruritus23.03.12.0010.015743%
Pyrexia08.05.02.0030.013119%
Rash23.03.13.0010.019416%Not Available
Seizure17.12.03.0010.007871%
Syncope02.11.04.015; 24.06.02.012; 17.02.04.0080.007871%
Therapeutic response unexpected08.06.01.0010.014168%Not Available
Tremor17.01.06.0020.010495%
Urticaria23.04.02.001; 10.01.06.0010.005248%
Vomiting07.01.07.0030.028862%
Toxic skin eruption12.03.01.073; 23.03.05.003; 10.01.01.0080.005248%Not Available
Skin toxicity23.03.03.032; 12.03.01.0200.005248%Not Available
Liver function test increased13.03.04.031--Not Available
Somatic symptom disorder19.24.01.0060.005248%Not Available
Heavy menstrual bleeding21.01.03.005--Not Available
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