Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Meclofenamate sodium
Drug ID BADD_D01363
Description A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Indications and Usage For the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.
Marketing Status approved; vet_approved
ATC Code M01AG04; M02AA18
DrugBank ID DB00939
KEGG ID D00169; D08162
MeSH ID D008469
PubChem ID 4038
TTD Drug ID D08IFL
NDC Product Code 0378-3000; 49452-4397; 22568-1018; 0378-2150; 63126-301
UNII 94NJ818U2W
Synonyms Meclofenamic Acid | Meclofenamate Sodium Anhydrous | Benzoic acid, 2-((2,6-dichloro-3-methylphenyl)amino)-, monosodium salt, monohydrate | Meclofenamate Sodium | Sodium Meclofenamate | Meclofenamate, Sodium | Meclofenamate Sodium Monohydrate | Meclofenamate | Meclomen
Chemical Information
Molecular Formula C14H10Cl2NNaO2
CAS Registry Number 6385-02-0
SMILES CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)[O-])Cl.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Insomnia19.02.01.002; 17.15.03.002--
Iritis10.02.01.022; 06.04.03.002--Not Available
Jaundice cholestatic09.01.01.005--Not Available
Leukopenia01.02.02.001--Not Available
Liver function test abnormal13.03.04.030--Not Available
Macular oedema06.04.06.005--Not Available
Malaise08.01.01.003--
Nausea07.01.07.001--
Neutropenia01.02.03.004--Not Available
Nocturia20.02.03.001--Not Available
Oedema08.01.07.006; 14.05.06.010--Not Available
Palpitations02.11.04.012--
Paraesthesia23.03.03.094; 17.02.06.005--
Peptic ulcer07.04.07.001--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Retinal disorder06.08.03.005--Not Available
Serum sickness12.02.08.004; 10.01.03.004--
Serum sickness-like reaction10.01.03.005; 08.01.03.003--Not Available
Stevens-Johnson syndrome11.07.01.005; 10.01.01.045; 23.03.01.007; 12.03.01.014--
Stomatitis07.05.06.005--
Systemic lupus erythematosus23.03.02.006; 15.06.02.003; 10.04.03.004--Not Available
Thrombocytopenic purpura01.08.01.003; 23.06.01.007--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Ulcer08.03.06.001--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vision blurred06.02.06.007; 17.17.01.010--
Visual acuity reduced06.02.10.012; 17.17.01.011--
Vomiting07.01.07.003--
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