Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Mefenamic acid
Drug ID BADD_D01368
Description A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Indications and Usage For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Marketing Status approved
ATC Code M01AG01
DrugBank ID DB00784
KEGG ID D00151
MeSH ID D008528
PubChem ID 4044
TTD Drug ID D05FTJ
NDC Product Code 80425-0306; 51552-1367; 58747-0601; 62250-677; 62350-0015; 49452-4398; 52935-0008; 51927-4457; 0276-0509; 38779-0669; 42571-258; 68180-185; 22365-117
UNII 367589PJ2C
Synonyms Mefenamic Acid | Acid, Mefenamic | Mefenaminic Acid | Pontal | Contraflam | Coslan | Parkemed | Ponstan Forte | Ponsyl | Dysman | Mefac | Mefacit | Nu-Mefenamic | Nu Mefenamic | Pinalgesic | PMS-Mefenamic Acid | PMS Mefenamic Acid | Ponalar | Ponalgic | Ponmel | Ponstan | Ponstel | Mefic | Apo-Mefenamic | Apo Mefenamic
Chemical Information
Molecular Formula C15H15NO2
CAS Registry Number 61-68-7
SMILES CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lymphadenopathy01.09.01.002--Not Available
Malaise08.01.01.003--
Melaena24.07.02.013; 07.12.02.004--Not Available
Meningitis17.06.03.001; 11.01.03.001--
Meningitis aseptic17.06.03.002; 11.01.03.002--Not Available
Myocardial infarction02.02.02.007; 24.04.04.009--
Nausea07.01.07.001--
Nephrotic syndrome20.05.01.002--
Nervousness19.06.02.003--Not Available
Neurotoxicity17.02.10.002; 12.03.01.0110.002974%Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Oesophagitis07.08.05.001--
Oliguria20.01.03.004--Not Available
Pain08.01.08.004--
Palpitations02.11.04.0120.002974%
Pancreatitis07.18.01.001--
Pancytopenia01.03.03.003--Not Available
Paraesthesia23.03.03.094; 17.02.06.005--
Peptic ulcer07.04.07.001--Not Available
Periorbital oedema06.08.03.017; 23.04.01.002; 10.01.05.0100.002974%
Photosensitivity reaction23.03.09.003--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Polyuria20.02.03.002--Not Available
Proteinuria20.02.01.011--
Pruritus23.03.12.001--
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rectal haemorrhage24.07.02.018; 07.12.03.001--
Renal failure20.01.03.005--Not Available
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